Hormone replacement therapy in women with cancer and risk of cancer-specific mortality and cardiovascular disease: a protocol for a cohort study from Scotland and Wales

Abstract Background Hormone replacement therapy (HRT) is widely used and has proven benefits for women with menopausal symptoms.An increasing number of women with cancer experience menopausal symptoms but the safety of HRT use in women with cancer is unclear.There are particular concerns that HRT could accelerate cancer progression in women with ca

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Genotoxic changes in peripheral lymphocytes after therapeutic exposure to crude coal tar and ultraviolet radiation

Aims: Goeckerman therapy is based on combined exposure to Time Release Dispensers UV radiation (UVA, UVB) and crude coal tar (PAHs).Some indicators suggest a genotoxic hazard, however, the level of genotoxic risk of the therapy has not yet been investigated sufficiently.This study aims to assesss the genotoxic risk.Methods: The studied group consis

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Estimating the time of Highly Pathogenic Avian Influenza virus introduction into United States poultry flocks during the 2022/24 epizootic.

Following confirmation of the first case of the ongoing U.S.HPAI H5N1 epizootic in commercial poultry on February 8, 2022, the virus has continued to devastate the U.S.poultry sector and the pathogen has since managed to cross over to livestock and a few human cases have also been reported.Efficient outbreak management benefits greatly from timely

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